Grubbs Catalyst 1st Generation
Synonym: Benzylidene-bis(tricyclohexylphosphine)dichlororuthenium, Bis(tricyclohexylphosphine)benzylidine ruthenium(IV) dichloride, Dichloro(benzylidene)bis(tricyclohexylphosphine)ruthenium(II), Grubbs Catalyst® C823
Formula : C43H72Cl2P2Ru
Molecular weight : 822.96 g/mol
CAS-No. : 172222-30-9
assay: 97%
Form: solid
Storage:
Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature 2 - 8 °C
Air and light sensitive. Handle and store under inert gas.
Storage class (TRGS 510): 4.1B: Flammable solid hazardous materials
Application
First metathesis catalyst to be widely used in organic synthesis. Useful in Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, in Olefin cross metathesis (CM) and Ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions. Used to form stapled peptides.
Hazard statement(s)
H228 Flammable solid.
